Stone Eight

The partnership ranging from eating plan, opportunity balance and you can fertility into the males

Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.


The frequency out-of infertility certainly one of people out-of reproductive age ranges, centered on individuals offer, away from 8% to 25% [1–3]. Men sterility is the only reason for infertility for the 20–30% out-of cases and you can a very important factor leading to sterility when you look at the 50% of all sterility circumstances . The fresh new testing from male potency always includes scientific test and you can review to your resource beliefs of one’s following sperm variables: frequency, total sperm count, attention, motility and you can morphology (Desk 1) . Reasonable sperm fertility and you may/otherwise top quality is available inside ninety% from lovers having virility difficulties . From the evaluation from virility, the brand new concentrations of men reproductive hormones also are analyzed. More recently, the latest molecular constitution away from cum muscle, examined by the comparing the amount of DNA fragmentation otherwise oxidative stress has been all the more taken into consideration. Several training utilize the DNA fragmentation list (DFI) because an indicator of pregnancy success. Centered on Evenson and Wixon, DFI selections from 3 to 5% from inside the healthy males, when you find yourself a DFI from ? 30% try associated with faster virility . Already outlined genetic situations, and both chromosomal aberrations and monogenic alter, account fully for only about 10–15% out-of instances of men sterility . The source to own fertility issues could be environment factors. The goal of the research was to analyze the relationship ranging from diet plan, opportunity balance and you may virility rates in males.

Means out of literary works look

A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.

Semen factor Source limitation (95% trust times)
Sperm regularity 1.5 ml (1.4–step one.7)
Complete sperm count 39 mil for each ejaculate (33–46)
Cum concentration 15 million for each and every ml (12–16)
Efforts 58% real time (55–63)
Progressive motility 32% (31–34)
Overall (progressive + nonprogressive) motility 40% (38–42)
Morphologically normal variations cuatro.0% (step three.0–4.0)

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